WebHydrogels are widely used as in vitro culture models to mimic 3D cellular microenvironments. The stiffness of the extracellular matrix is known to influence cell phenotype, inspiring work toward unraveling the role of stiffness on cell behavior using hydrogels. However, in many biological processes such as embryonic development, … WebAug 24, 2024 · Furthermore, on-demand control of the hydrogel stiffness was achieved by an on-demand stimulus of heating. ... “Dynamic phototuning of 3D hydrogel stiffness,” Proceedings of the National …
Design and Applications of Photoresponsive Hydrogels
WebDynamic modulation of stiffness can be induced at least 14 d after gelation and can be spatially controlled to produce gradients and patterns. We use this system to investigate … WebAug 24, 2024 · Short-term temporal modulation of hydrogel moduli, a key factor of the substrates for cell development, was demonstrated and could provide dynamic … how many pets are insured in the us
Dynamic phototuning of 3D hydrogel stiffness [Applied Biological ...
WebMay 30, 2024 · Here, we utilize a dynamic 3D hydrogel capable of dynamic stiffening to interrogate the role of matrix stiffening on the invasive transformation of mammary epithelial cells. ... Dynamic phototuning of 3D hydrogel stiffness. PNAS. 2015; 2: 201421897. Google Scholar. OpenURL Placeholder Text WebDynamic phototuning of 3D hydrogel stiffness, PNAS, 2015 Stress relaxing hyaluronic acid-collagen hydrogels , Biomaterials, 2024 Elucidating the ECM-Epigenome connection WebOct 1, 2024 · Synthetic hydrogels with well-defined mechanical properties and chemical composition avoid the use of supraphysiologically stiff substrates [26] and, more recently, dynamic hydrogels that can be physically softened [[27], [28], [29]] or stiffened [30, 31] in the presence of cells mimic changes of stiffness in vivo. Dynamic hydrogels can ... how many pets are euthanized yearly in canada