Human bcma uniprot

Author: evau

August undefined, 2024

http://gnpbio.com/index.php/products/349/11/recombinant-proteins-enzymes/human-bcma-protein-ecd-extracellular-domain-fc-fusion-recombinant-detail WebCD269, also known as B cell maturation antigen (BCMA), is a 27 kD, single pass transmembrane protein with one TNFR-Cys repeat on its extracellular domain. CD269 is …

CXCR4 and anti-BCMA CAR co-modified natural killer cells …

WebBCMA is a human gene expressed preferentially in mature B lymphocytes as a 1.2 kb mRNA, which encodes a 184 amino acid peptide (BCMAp). The study of BCMA mRNA … WebELISA Human TNFRSF17 ELISA Kit (BCMA) (ab213840) Primary Anti-BCMA antibody [EPR22457-260] (ab253242) Protein Native Human IgG2 protein (ab90284) View more … hutchinson \u0026 bloodgood

Evaluation of B cell maturation antigen as a target for …

WebScientific Data. Bioactivity View Larger. Recombinant human BCMA / TNFRSF17 ( 193-BC) inhibits APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. The ED 50 for … WebUniProt ID: Q02223 : Source: Purified from ascites. Species reactivity: Human : Crossreactivity: Does not cross-react with mouse BCMA. ... The extracellular domain of … WebThe extracellular domain of human BCMA (aa 2-54) is fused at the C-terminus to the Fc portion of human IgG1. UniProt ID: Q02223 : Concentration: 1mg/ml after reconstitution. … hutchinson \\u0026 bloodgood

Effective Targeting of Multiple B-Cell Maturation …

WebRecombinant CHO-K1 cells constitutively expressing both the human BCMA protein (B-Cell Maturation Antigen or CD269, GenBank accession #NM_001192) and the Gaussia … WebUniprot ID: Q02223. Description: Recombinant human BCMA protein with C-terminal human Fc and 6×His tag. Expression Host: HEK293. Delivery: In Stock. Molecular … mary semonin obituaryWebRecombinant Human BCMA protein (ab139210) Datasheet SDS Submit a review Submit a question $420 Add to basket Shipping info to United States View Boston delivery areas … hutchinson tv stand with fireplace

"Web2 Mar 2024 · B-cell maturation antigen (BCMA, TNFRSF17) is a confirmed cell surface target for MM. BCMA is expressed on malignant plasma cells from patients with MM, with normal tissue expression limited primarily to plasma cells and a subset of activated B cells. 18 Multiple BCMAxCD3 bsAbs and anti-BCMA CAR T cells are being tested in the clinic … " - Human bcma uniprot

Human bcma uniprot

Web19 Nov 2007 · B-cell maturation antigen (BCMA) is expressed on normal and malignant plasma cells and represents a potential target for therapeutic intervention. BCMA binds to two ligands that promote tumor cell survival, a proliferation inducing ligand (APRIL) and B-cell activating factor. Web14 Apr 2024 · Abstract. Background: The introduction of novel targeted therapies and immunotherapies has dramatically improved responses and overall survival in multiple …

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WebUseful information about the gene from Entrez. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in … WebHuman BCMA/TNFRSF17 quantitates human BCMA/TNFRSF17 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human …

WebImmobilized BCMA at 2 μg/ml can bind Anti-BCMA recombinant antibody, the EC50 of human BCMA protein is 1.912-2.488 ng/ml.②Measured by its binding ability in a … WebBCMA (mouse):Fc (human) (recombinant protein) - Order from Adipogen Home BCMA (mouse):Fc (human) (rec.) BCMA (mouse):Fc (human) (rec.) AG-40B-0076-C050 50 µg CHF 240.00 AG-40B-0076-3050 3 x 50 µg CHF 480.00 Size Qty Add to Cart Contact Us! Specifications / Handling Description

WebSpecificity This antibody recognizes human BCMA (B Cell Maturation Protein). BCMA is a receptor for BAFF and April, two novel members of the TNF superfamily of proteins … Web21 Mar 2016 · TNFRSF17 (TNF Receptor Superfamily Member 17) is a Protein Coding gene. Diseases associated with TNFRSF17 include Lymphoma and Macroglobulinemia.Among …

WebThe Pathology section contains mRNA and protein expression data from 17 different forms of human cancer. Correlation analysis based on mRNA expression levels of human …

Web11 Aug 2009 · Having observed that Xenopus Fn14 cross-reacts with human TWEAK, despite its relatively low sequence homology to human Fn14, we examined the … hutchinson tyres mtbWebConstruct Details: The recombinant human BCMA-Fc fusion is expressed as a 281 amino acid protein consisting of Leu2 - Ala54 region of BCMA (UniProt accession #Q02223) … hutchinson \\u0026 bloodgood llpWebThe BCMA / NF-κB - HEK293 recombinant cell line has been transfected with full-length human BCMA cDNA (Genbank #NM_001192) under control of a CMV promoter for high … hutchinson \u0026 buchananWebPSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer … mary semonich holvaWebChimeric antigen receptor (CAR) T cell immunotherapy for multiple myeloma (MM) is currently becoming standard of care in advanced MM. 1 2 Most approaches currently focus on targeting B cell maturation antigen (BCMA) as a single target because BCMA is critical for maintaining tumor cell phenotypes and expression is limited to the B and plasma cell … maryse monday night rawWebThe human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, … maryse mizanin youngerWeb5 Feb 2024 · B-cell maturation antigen (BCMA), a cell surface receptor recognizing B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL), play an important role in the survival of long-lived PCs in the bone marrow ( 14–17 ). BCMA is expressed on PCs and is highly expressed on myeloma cells while being absent on most other cells ( 18 ). hutchinson \u0026 bloodgood el centro